Description
Product Characteristics: Function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion.
Subcellular location: Membrane, Multi-pass membrane protein. Also known as: Short transient receptor potential channel 7, transient receptor potential cation channel, subfamily C, member 7, TrpC7, Transient receptor protein 7, Mtrp7, Receptor-activated cation channel TRP7.
Target Information: non-selective cation channel\, activated down-stream of G-protein-coupled receptors [RGD, Feb 2006]